What is Tuberculosis and Hepatitis. Explain briefly?

Tuberculosis 

Tuberculosis (TB) is a serious infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily targets the lungs, where it leads to symptoms such as a chronic cough, chest pain, hemoptysis (coughing up blood), fever, night sweats, and significant weight loss. Although TB mainly affects the lungs, it can also involve other parts of the body, such as the kidneys, spine, or brain, known as extrapulmonary TB. The infection spreads through airborne droplets released when an infected person coughs or sneezes. Diagnosing TB involves a combination of tests, including the Mantoux tuberculin skin test, which checks for an immune response to TB antigens, and chest X-rays to identify lung damage. Sputum samples are also analyzed to confirm the presence of TB bacteria. Treatment generally involves a multi-drug regimen, including antibiotics such as isoniazid, rifampin, ethambutol, and pyrazinamide, over a period of at least six months. In cases of drug-resistant TB, more complex and prolonged treatments are required. Prevention strategies include the BCG vaccine, which is particularly effective in children, and implementing infection control measures like proper ventilation and the use of masks.

 Hepatitis 

Hepatitis encompasses a range of liver inflammations caused by various viruses, including Hepatitis A, B, C, D, and E. Hepatitis A is usually contracted through the consumption of contaminated food or water and is characterized by symptoms such as fatigue, abdominal pain, nausea, and jaundice. This type of hepatitis typically resolves with supportive care, and a vaccine is available for prevention. Hepatitis B, transmitted through exposure to infectious body fluids, can lead to both acute and chronic liver diseases. Chronic cases may require antiviral medications like tenofovir or entecavir, and prevention is facilitated by vaccination. Hepatitis C is predominantly spread through blood-to-blood contact and often results in chronic infection, potentially leading to severe liver damage. Advances in treatment, particularly with direct-acting antivirals (DAAs), have significantly improved cure rates. Hepatitis D is unique in that it only infects those who are already infected with Hepatitis B, and managing it involves treating Hepatitis B and preventing further complications. Hepatitis E is transmitted via contaminated water and is often self-limiting, though it can be more severe in pregnant women. Diagnostic approaches for hepatitis generally include blood tests to detect viral antigens or antibodies, liver function tests, and imaging studies like ultrasound or MRI. Treatment strategies vary based on the specific type of hepatitis and the severity of the disease, with a focus on antiviral medications, lifestyle modifications, and regular monitoring of liver health.

Tuberculosis and Hepatitis
Tuberculosis and Hepatitis



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